Purpose. To report the risk of methicillin-resistant Staphylococcus aureus (MRSA) ocular infection after UVA-riboflavin corneal\ncollagen cross-linking in a patient with atopic dermatitis. Methods. A 22-year-old man, with bilateral evolutive keratoconus and\natopic dermatitis, underwent UVA-riboflavin corneal cross-linking and presented with rapidly progressive corneal abscesses and\ncyclitis in the treated eye five days after surgery. The patient was admitted to the hospital and treated with broad-spectrum\nantimicrobic therapy. Results.The patient had positive cultures for MRSA, exhibiting a strong resistance to antibiotics. Antibiotic\ntherapy was modified and targeted accordingly. The intravitreal reaction is extinguished, but severe damage of ocular structures\nwas unavoidable. Conclusion. Riboflavin/UVA corneal cross-linking is considered a safe procedure and is extremely effective in\nhalting keratoconus� progression. However, this procedure is not devoid of infectious complications, due to known risk factors\nand/or poor patients� hygiene compliance in the postoperative period. Atopic dermatitis is a common disease among patients with\nkeratoconus and Staphylococcus aureus colonization is commonly found in patients with atopic dermatitis. Therefore, comorbidity\nwith atopic dermatitis should be thoroughly assessed through clinical history before surgery. A clinical evaluation within three days\nafter surgery and the imposition of strict personal hygiene rules are strongly recommended.
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